Thus the g k Nnte IR radiation, lead to different effects of point mutations in severe damages caused to genetic material, dependent Ngig on the dose of radiation. Cancer incidence and varies with the type of radiation, the radiation from radon is still tons more harmful radiation from low linear energy transfer, such as gamma and X IR-induced Sch To either by direct interaction with macromolecules, so that they ionizing or indirectly through the formation of free radicals, the lockable end process of Sch perform the. Damage imposed Dinner entered in the induction of cellular have Ren repair process, if the damage is detected. The damage, if too severe to be repaired and the cell initiates the process of programmed cell death. In general, a low dose of IR leads to the induction of DNA-Sch Ending in the t Dlichen and not repaired with time, mounted, such as a mutation. This has an r Important in the development of carcinogenesis, then it makes a potential risk for cancer. From radiation, the difference for the effective treatment and treatment of malignant tumors on the basis of the same principle has been used. Radiation therapy uses essentially the differences in proliferative potential as the essential characteristic of the distinction between normal and cancer cells. It is used by more than 100 years for almost all solid tumors. Radiotherapy is a treatment approach for localized and therefore affects only the parties who are caught in the area of treatment. Nearly 60% of patients with radiation therapy as Behandlungsm Nelarabine DNA Synthesis inhibitor Possibility at some point may need during the illness.
It is currently used for localized tumors such as cancer of the skin, brain, breast, prostate, Geb treat Rmutterhals, and can also be used to Leuk To treat anemia, lymphoma and glial tumors, with the latter, the tumor is on the h ufigsten prime dealt with separately from adult therapy. In the treatment of cancer, radiation therapy delivers packets of energy in the form of photons or particles in a predetermined tumor volume. Clinically, the IR typically in the form of photons of energy in the wavelength Ngenbereichen X-rays of the electromagnetic spectrum and is supplied in the form of particles in the form of electrons. Beautiful to, which is caused by the supply of R Ntgenstrahlen indirectly, either to create the production of fast electrons, the ionization events, which was directly damage macromolecules such as DNA, or collide with molecules of water in the cell caused the spontaneous generation of radicals from superoxide, singlet oxygen species, hydroxyl, peroxy radical and nitric oxide Rest The radiation is in the fractions t been happy as a single dose, allowing normal trilostane cells time to repair and re-created between the individual therapy session therefore minimal damages caused to healthy cells. Recently, the use of proton beams ntgenstrahlen R Was preferred because of the advantage that the proton beam therapy of the M Possibility, h Deliver higher doses of radiation beams molded directly into the tumor while minimizing dose has normal tissues. This results in fewer side effects and improved survival rates. Despite the increased Hten accuracy, sensitivity, and the technological progress, the successful treatment of cancer patients with radiotherapy h Depends largely on the sensitivity of the tumor to radiation.