“
“A series of acrylic monomers-starch graft copolymers were prepared by ceric ion initiation method by varying the amount of monomers. These graft copolymers

were characterized by IR and (13)C-NMR spectroscopy. PI3K inhibitor It was seen that as the concentration of monomer [acrylic acid (AA), methacrylic acid (MA), and methyl methacrylate (MMA)] increased the percent add-on increased in all the graft copolymers, whereas grafting efficiency increased initially but showed a slight decrease with further increase in the monomer concentration (except for MMA). The release rate of paracetamol as a model drug from graft copolymers as well as their blends was studied at two different pH, 1.2 and 7.4, spectrophotometrically. The release of paracetamol in phosphate buffer solution at pH 1.2 was insignificant in the first 3 h for St-g-PAA- and St-g-PMA-graft copolymers, which was attributed to the matrix compaction and stabilization through hydrogen bonding at lower pH. At pH 7.4, the release rate was seen to decrease with increase in add-on. The tablet containing poly(methyl methacrylate) (PMMA) did not disintegrate at the end of 30-32 h, which may be attributed to the hydrophobic nature of PMMA. These results indicate that the graft copolymers may be useful to overcome the harsh environment MK 2206 of the stomach and can be used as excipients in colon-targeting matrices.

(C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 114: 2893-2900, 2009″
“Tracheal aspirates were collected from 176 hospitalized antibiotic-pretreated children with community-acquired pneumonia. Haemophilus influenzae and Streptococcus pneumoniae were detected by both culture and target-enriched multiplex (TEM)-PCR whereas Mycoplasma pneumoniae and Chlamydia pneumoniae were detected by TEM-PCR Only. TEM-PCR detected more S. pneumoniae (32 vs. 7) and H. influenzae (29 vs. 23) than did culture. TEM-PCR detected

an additional 26 M. pneumoniae and 1 C pneumoniae. TEM-PCR significantly enhances the pathogen-specific diagnosis of CAP in children.”
“The Cu-doped SnO2 nanowires (NWs) with average diameter of 40-100 nm were synthesized by thermal chemical vapor transport method. High-resolution transmission electron microscopy and Metabolism inhibitor energy dispersive spectroscopy studies of Cu-doped SnO2 NWs demonstrate that the NWs are single-crystal structures and Cu is homogeneously doped into the SnO2 lattice. X-ray photoelectron spectroscopy measurements evidence the existence of divalent Cu ions (Cu2+). Although the NWs consist of only nonmagnetic elements, room-temperature ferromagnetism is observed and its origin is attributed to both the structure defects and strong p-d ferromagnetic coupling between the local magnetic moment of Cu2+ and the polarized valence electrons of the surrounding oxygen based on first-principles calculations.