6B, images corresponding to the Control (control medium) and to HB-EGF + Gefitinib were substituted for a panel belonging to Fig. 6A. The corrected

versions of Figure 5C and 6B are provided below. The publisher regrets the error. “
“Distress in infancy is often related to abdominal symptoms or feeding. Infantile “colic” is very common and transient, and may be improved treating by associated gastro-oesophageal reflux and/or food allergy. An approach to assessment is described, aiming to identify rarer or less benign conditions, including a directed clinical examination and key investigations. “
“This chapter provides an approach to the immediate assessment and differential diagnosis of upper and lower gastrointestinal bleeding, with blood selleck chemical test and imaging investigations. “
“A 36-year-old man presented with two weeks of intermittent dull upper abdominal pain, fever and rigors.

He had no significant medical history and no previous surgical history. On examination, he was febrile (38°C) with severe tenderness over the upper abdomen. Laboratory examination disclosed marked elevated white blood cell count of 24,140/µL (normal range 3,500–9,100/µL). Abdominal sonography disclosed a heterogeneous mass over left lobe of the liver with a linear hyperechoic material in it (Figure 1, arrow). An abdominal computed tomography revealed a multi-cystic BAY 73-4506 research buy lesion in left lobe of the liver with a linear calcified material within (Figure 2). The findings of sonography and computed tomography check details suggested a pyogenic liver abscess associated with a penetrating fish bone. After controlling the sepsis, this patient was referred to the surgical department and the penetrating fish bone was removed. Perforation occurs in less than 1% of all cases of ingested foreign bodies. Perforation can occur at any level of the alimentarytract,

and the commonest site is the terminal ileum. A fish bone is the commonest type of foreign body causing gastrointestinal perforation. Liver abscess is a rare but potentially fatal complication of fish bone penetration. Less than 20 cases have been documented in the literature. The diagnosis is suggested by abdominal computed tomography showing the linear hyperattenuating structure within the abscess. The initial treatment of liver abscess caused by a penetrating fish bone includes both drainage and antibiotic therapy. Although medical therapy alone had been reported to be successful, surgical or percutaneous transhepatic removal of the fish bone remains the treatment of choice in the literature to prevent recurrence. Contributed by “
“Clinical perspectives in hepatology aims to engage two experts with opinions supporting differing perspectives on the management of a case. Typically, the case represents an area of debate or evolving practice in clinical hepatology. The case described by Drs.