The fire performance of the coated GRE

composite was studied by cone calorimetry at 35 and 50 kW/m(2) heat fluxes. While the sample with similar to 500 mu m thick coating did not ignite at both heat fluxes, the one with the similar to 300 mu m thick coating ignited at 50 kW/m(2), Elacridar however the time-to-ignition was delayed from 60s in the uncoated sample to 195 s and the peak heat release rate reduced from 572 kW/m(2) to 86 kW/m(2). The coatings did not peel off when subjected to a tape pull test and resisted cracking/debonding during an impact drop test of up to 5 J energy. However, the coatings are hydrophilic, showing significant mass loss in a water soak test. The improvement of the hydrophobicity of these coatings is a focus of our future research. (C) 2014 Elsevier B.V All rights reserved.”
“To gain a global view of the genomic response of neurons to normobaric and hyperbaric hyperoxic stress, we performed a microarray analysis of gene expression after exposure to varying levels of partial oxygen pressures. Rat neurons were exposed to normobaric hyperoxia, hyperbaric (2, 4, and 6 atmosphere

absolute) air or hyperbaric O(2). We identified 183 genes significantly altered (increased or decreased a parts per thousand yen1.5-fold) in response to pressure and/or oxidative stress. Among them, 17 genes changed in response to all exposure conditions. More genes were altered in response to hyperbaric air than hyperbaric O(2). The altered genes included factors associated with stress responses,

selleck chemical transport/neurotransmission, signal transduction, and transcription factors. HDAC inhibitor The results may serve as guidance for selection of biomarkers of hyperoxia and hyperbaric O(2) response and provide a starting point for further studies to investigate the global molecular mechanisms underlying hyperbaric oxidative stress.”
“In the present study toxic effects of active molluscicidal component of Areca catechu and Carica papaya was studied on certain enzymes in the nervous tissue of freshwater snail Lymnaea acuminata. In in vivo and in vitro exposure of arecoline (active component of Areca catechu seed) and papain (C papaya latex and seed) significantly inhibited the acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activity in the nervous tissue of L. acuminata. The inhibition kinetics of these enzymes indicate that arecoline and papain caused competitive and uncompetitive inhibition of AChE, respectively, whereas arecoline caused competitive-non-competitive inhibition of ACP/ALP and papain caused non-competitive inhibition of ACP/ALP. Thus the inhibition of AChE, ACP and ALP by arecoline and papain in the nervous tissue of L. acuminata may be the cause of molluscicidal activity of A. catechu and C. papaya, respectively. (C) 2008 Elsevier Inc. All rights reserved.