The availability of most of these drugs makes it easy for the clinician to find an appropriate treatment for most patients. Unfortunately, in the daily practice, osteoporosis treatment too often consists of drug prescription, without any other preventive or therapeutic measure. Besides drug prescription, non-pharmacological osteoporosis management is an important and very broad concept. It must be considered as part of the long-term prevention of fractures, for men and for women,

GSK1904529A not only for postmenopausal women, but from childhood through adolescence, pre- and perimenopause. This topic also BKM120 order includes the surgical or invasive procedures for the treatment of peripheral and vertebral fractures and the post-fracture rehabilitation. Lifestyle habits including calcium intake, general nutrition and weight-bearing exercise during adolescence and early adulthood contribute up to 20% of the observed variation in the attainment of peak bone mass, as well as to the rate of bone loss later in life [4, 5]. Falls

in the elderly are a major health problem, contributing to significant increase in fracture risk, morbidity, and even mortality [6]. Fall prevention is consequently important in the elderly as nearly one out of three adults living in the community falls at least once each year, the risk being from

far more important for institutionalized patients or those with neurologic disturbances [7]. In the context of patients with high risk of falls, the use of hip protectors, aimed at reducing the impact of falls onto the hip, has been suggested as an effective strategy for hip fracture in nursing home residents and FK228 nmr potentially among other high-risk individuals [8]. Vertebroplasty and kyphoplasty through percutaneous injection of bone cement into fractured vertebral bodies have been proposed for short- and long-term Tacrolimus (FK506) pain management. For many years, results of these surgical procedures have been evaluated positively in retrospective non-randomized trials but results of recent controlled studies are becoming available [9, 10]. The present document is the result of a national consensus, based on a systematic review and a critical appraisal of the literature. It aims at providing clinicians with an overview of the currently available non-pharmacological measures for the prevention and treatment of osteoporosis in men and women.