Stability trials up to 6 months displayed excellent reproducibili

Stability trials up to 6 months displayed excellent reproducibility.”
“Purpose The aim of the study was to examine patient-reported symptoms and self-care strategies in Thai patients with cancer

Methods The study was descriptive using a cross-sectional design It was carried out at the National Cancer Institute Thailand (Bangkok Lopburi) 202 patients undergoing combined

radiotherapy and chemotherapy (RT-CT) n = 52 or CT alone n = 103 or RT alone n = 47 participated Data was collected with the use of a 25-item Therapy-Related Symptom Checklist TRSC (Thai) a Self-Care Method scale the Karnofsky Scale and a Health Data form

Results Patients on combined RT-CT reported more symptoms on the TRSC with greater severity than P505-15 those receiving RT or CT alone (F = 72 p < 0 01) and lower Karnofsky score (F = 42 p < 0 05) Karnofsky and TRSC scores were inversely correlated Using complementary care categories self-care methods reported were six types (a) Diet/nutrition/life-style changes (e g modify food) to manage Eating and Fatigue symptoms (b) Mind/Body Control to relieve Fatigue and other symptoms (c) Biologic treatment (e g vitamins) for eating

difficulties (d) SHP099 Herbal treatments for hair loss (e) Other methods and (f) taking prescribed medicines to control pain and other symptoms Some patients reported doing nothing as coping

Conclusions Self-care Including complementary care use as an adjunct to cancer treatments could help patients deal with the side effects of therapy Assessment of symptoms using the TRSC (Thai) version and their alleviation could enable the health care providers to enhance patients

coping during cancer treatments (c) 2010 Elsevier Ltd All rights reserved”
“The “”endocannabinoid system (ECS)”" comprises the endocannabinoids, the enzymes that regulate their synthesis and degradation, the prototypical cannabinoid WZB117 in vitro receptors (CB1 and CB2), some noncannabinoid receptors, and an, as yet, uncharacterised transport system. Recent evidence suggests that both cannabinoid receptors are present in sex steroid hormone-dependent cancer tissues and potentially play an important role in those malignancies. Sex steroid hormones regulate the endocannabinoid system and the endocannabinoids prevent tumour development through putative protective mechanisms that prevent cell growth and migration, suggesting an important role for endocannabinoids in the regulation of sex hormone-dependent tumours and metastasis. Here, the role of the endocannabinoid system in sex steroid hormone-dependent cancers is described and the potential for novel therapies assessed.”
“The effects of terpenes on the release and permeation of ofloxacin and lidocaine from moisture-activated composite patches were investigated. Ofloxacin without enhancers showed very low permeation rate (0.58 g/cm2/hr), and the addition of cineole enhanced the permeation flux 14.1-times; /-menthol and d-limonene increased it 4.7- and 3.5-times, respectively.

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