Slit-lamp examination of nilotinib hcl the left eye was notable for 2+ ciliary injection and for 2+ anterior chamber cell and flare accompanied by scattered mutton fat and stellate keratic precipitates in Arlt��s triangle. No hypopyon was observed. She was noted to have an intumescent cataract with a prominent vertical cleft (Figure 1). There was no anterior bowing of the iris, and the angle was open to the scleral spur without synechiae on gonioscopy. Figure 1 A, Intumescent cataract with prominent vertical cleft. B, Retro-illumination of cornea demonstrating stellate and mutton fat keratic precipitates. The anterior segment examination of her right eye was unremarkable. Dilated fundus examination revealed a sharp, pink disc with a 0.4 cup-to-disc ratio and a healthy fundus.

There was no posterior view in the left eye due to the density of her cataract. Ancillary Testing A B-scan ultrasound of the right eye revealed small, scattered vitreous opacities without cyclitic membranes or vitreoretinal Inhibitors,Modulators,Libraries adhesion, consistent with mild-to-moderate Inhibitors,Modulators,Libraries inflammation. There was no evidence of large lens fragments, recurrent retinal detachment, or choroidal thickening. Treatment A laboratory workup for anterior uveitis was deferred given the patient��s recent surgery and the fact that this was her sentinel inflammatory episode. Based on her ultrasound findings and the lack of profound pain or hypopyon, it was not thought necessary to perform immediate vitreous and/or aqueous tap for gram stain and culture. The patient was initially placed on prednisolone 1% eyedrops every hour, along with brimonidine, dorzolamide, timolol, and cyclopentolate drops.

After one week of treatment, the patient��s IOP dropped to within normal range and her eye appeared less injected. Subjectively, she was more comfortable but had persistent 1+ to 2+ cell on her anterior segment examination. Differential Diagnosis The differential diagnosis Inhibitors,Modulators,Libraries for Inhibitors,Modulators,Libraries our patient included inflammatory causes such as granulomatous Inhibitors,Modulators,Libraries anterior uveitis (either exacerbated by surgical intervention or coincidental to it), anterior segment ischemia from a tight scleral buckle, or protracted postoperative inflammation. The last two conditions, however, would not be expected to produce typical mutton fat keratic precipitates. As a health care worker, she had PPDs placed annually and had always been nonreactive.

Based on her ethnicity, the patient was at low risk for sarcoid. Lyme disease is rare in Miami, and she did not have a history of recent Brefeldin_A travel to endemic areas. She did not practice high-risk sexual behavior or report any stigmata of syphilis. Likewise, she did not have any respiratory or genitourinary symptoms consistent with Wegener��s granulomatosis. Toxoplasmosis was also considered unlikely because her B-scan ultrasound did not reveal evidence of significant posterior uveitis.