Proposed Ma took It is the aim of this systematic review and meta-analysis, the administration of androgens and androgen-modulating substances on the likelihood of achieving pregnancy in poor responders ovarian stimulation subjected to review with gonadotropin-releasing hormone analogs and gonadotropins for IVF. Search strategy Methods A literature search MEDLINE, GSK1838705A EMBASE, CENTRAL, ISI Web of Science and Scopus for the period ending April 2011 was independent of two ngigen people can be held to RCTs that identify the following question assessed Is if the administration of testosterone or DHEA or aromatase inhibitors or recombinant LH or hCG increased ht the probability of pregnancy in poor responders undergoing ovarian stimulation with GnRH analogues and gonadotrophins for IVF For this purpose, a research strategy with key words to three terms in each case was identified.
These conditions include, intervention, Bev Lkerung, and, framework, various synonyms describing each semester were presented as free text words in electronic databases in order to maximize the sensitivity of the search strategy. In addition have been citations lists of all relevant publications GDC-0449 and review articles on manual searches. Conduct of the meeting of the Europ European Society of Human Reproduction and Embryology and the American Society for Reproductive Medicine also be manually searched to identify relevant studies. No language RESTRICTIONS Website will have been applied. Selection criteria for study inclusion / exclusion of studies were established before the literature search.
Studies had to meet the following criteria: administration of androgens or androgen modulators in the intervention group, the inclusion of women in IVF undergone by gonadotropins and GnRH analogues for stimulation of Eierst CKE, the inclusion of women as poor response and a parallel design from need, would randomized comparison of patients in the comparison groups be used. Studies, the asymmetric response additionally Tzlich to the assessed in each study included, were excluded. All interventions were parallel RCTs evaluating relevant in the current systematic review and meta-analysis, which suggested the definition of poor ovarian response, and dose-response protocol, the type of gonadotropin contained injected or inserted type and protocol of GnRH analogues. Study selection was independent of two Performed ngigen experts.
Any discrepancies were gel discussion Be st. Data Extraction Data extraction was independently Ngig performed by two reviewers. Demographic, methodological, procedural: The following data were collected from each of the eligible studies. In case of disagreement between the two examiners of the data-extraction was discussion gel Be st. The primary results Re endpoint for the current meta-analysis of weight Hlt is the realization of pregnancy per patient randomized clinical pregnancy or live birth, brought in as an expression. Secondary Included re endpoints the duration of gonadotropin stimulation, total dose of gonadotrophins to stimulate the Eierst skirts necessary, the number of retrieved complex cumulus oocytes, number of embryos transferred, the number of metaphase II oocytes, deaf